產品名稱：Polyclonal Anti- CD9 antibody
- 產品編號
- BPA1022
- 產品規格
- 100ug
- 價格
- 來源
- Rabbit
- 交叉反應
- Human, mouse, rat
- 免 疫 原
- A synthetic peptide (conjugated with KLH) corresponding to near N-terminal of human CD9.
- 產品簡介
- 1. Katz F, Povey S, Parkar M, Schneider C, Sutherland R, Stanley K, Solomon E, Greaves M (Mar 1984). "Chromosome assignment of monoclonal antibody-defined determinants on human leukemic cells". Eur J Immunol 13 (12): 1008–1013.
2. Park, K R; Inoue T, Ueda M, Hirano T, Higuchi T, Maeda M, Konishi I, Fujiwara H, Fujii S (Mar. 2000). "CD9 is expressed on human endometrial epithelial cells in association with integrins alpha(6), alpha(3) and beta(1)". Mol. Hum. Reprod. (ENGLAND) 6 (3): 252–257.
3. François Le Naour et al (2000). "Severely Reduced Female Fertility in CD9-Deficient Mice". Science 287 (5451): 319–321.
4. Kathryn E. Runge et al (2007). "Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution". Developmental Biology 304 (1): 317–325.
- 產品別名
- -
- 產品成分
- 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
- 檢測范圍
- -
- 檢測樣品
- -
- 產品應用
- WB ；IHC-P；ICC；Flow Cyt
- 保存條件
- Store at 4°C after thawing (1 week). Aliquot and store at -20°C for long term (at least one year).
- 背景資料
- CD9 antigen is a protein that in humans is encoded by the CD9 gene.1 CD9 was found to be intensely expressed on the cell surface of the glandular epithelium throughout the menstrual cycle without any apparent differences in staining intensity. In addition, Western blotting analysis of the affinity-purified proteins confirmed that CD9 was associated with integrins beta 1, alpha 3 and alpha 6 in the human endometrium. CD9 may be an important regulator of these integrins in the human endometrium.2 This protein also seems to be a key part in the egg-sperm fusion during mammalian fertilization, as CD9 knocked-out mice gametes don't undergo fusion.3 CD9 is located in the microvillar membrane of the oocytes and also appears to intervene in maintaining the normal shape of oocyte microvilli.4
- 參考資料
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