產品名稱：Polyclonal Anti- Lamin B antibody
- 產品編號
- BTL1034
- 產品規格
- 100ug
- 價格
- 558.00
- 來源
- Rabbit
- 交叉反應
- Human, mouse, rat, rabbit, pig, cat, chicken
- 免 疫 原
- Purified Lamin B.
- 產品簡介
- Reactivity Human, mouse, rat, rabbit, pig, cat, chicken
Product Form Liquid
Immunogen Purified Lamin B.
- 產品別名
- -
- 產品成分
- -
- 檢測范圍
- -
- 檢測樣品
- -
- 產品應用
- WB(1:100-400) IHC-C(1:100-500) IHC-Fr(1:100-500)
- 保存條件
- -20°C一年,避免反復凍融。
- 背景資料
- Lamins are the major components of the nuclear lamina which underlies the nuclear envelope of eukaryotic cells , they are members of the intermediate filament protein family. Vertebrate lamins are classified into 2 types, A and B. Lamin B is expressed in all kinds of cells. It is a component of the interphase nuclear lamina, is required to maintain nuclear shape and mechanical integrity. Lamin B has a role in spindle assembly. Furthermore, lamin B was essential for the formation of the mitotic matrix that tethers a number of spindle assembly factors.
- 參考資料
- 1. Tsai, M.-Y., Wang, S., Heidinger, J. M., Shumaker, D. K., Adam, S. A., Goldman, R. D., Zheng, Y. A mitotic lamin B matrix induced by RanGTP required for spindle assembly. Science 311: 1887-1893, 2006. 2. Goldman, R. D., Gruenbaum, Y., Moir, R. D., Shumaker, D. K., Spann, T. P. Nuclear lamins: building blocks of nuclear architecture. Genes Dev. 16: 533-547, 2002. 3. Maeno, H., Sugimoto, K., Nakajima, N. Genomic structure of the mouse gene (Lmnb1) encoding nuclear lamin B1. Genomics 30: 342-346, 1995.
