產品名稱：Monoclonal Anti- GAPDH antibody
- 產品編號
- BTL1030
- 產品規格
- 100ug
- 價格
- 558 .00
- 來源
- Mouse
- 交叉反應
- Human, mouse, rat, dog, rabbit, pig, chicken Does not react with non-vertebrate and prokaryote species.
- 免 疫 原
- Recombinant human GAPDH protein.
- 產品簡介
- Reactivity Human, mouse, rat, dog, rabbit, pig, chicken
Does not react with non-vertebrate and prokaryote species.
Product Form Liquid
- 產品別名
- -
- 產品成分
- -
- 檢測范圍
- -
- 檢測樣品
- -
- 產品應用
- WB(1:100-1000) IP(1-2 μg per 100-500 μg of total protein. 1ml of cell lysate) IF(1:50-500) IHC(1:50-500)
- 保存條件
- -20°C一年,避免反復凍融。
- 背景資料
- Glyceraldehyde 3-phosphate dehydrogenase (abbreviated as GAPDH or less commonly as G3PDH) is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. GAPDH has recently been implicated in several non-metabolic processes, including transcription activation, initiation of apoptosis, and ER to Golgi vesicle shuttling.
- 參考資料
- 1. Meyer-Siegler, K., Mauro, D. J., Seal, G., Wurzer, J., deRiel, J. K., Sirover, M. A. A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase. Proc. Nat. Acad. Sci. 88: 8460-8464, 1991. 2. Zheng L, Roeder RG, Luo Y (2003). "S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component". Cell 114 (2): 255–66. 3. A. Tarze, A. Deniaud, M. Le Bras, E. Maillier, D. Molle, N. Larochette, N. Zamzami, G. Jan, G. Kroemer, and C. Brenner (2007). "GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization". Oncogene 26 (18): 2606–2620.
