
產品名稱:Monoclonal Anti-Tag-100 Tag antibody
- 產品編號
- BTL1021
- 產品規格
- 100ug
- 價格
- 700.00
- 來源
- Mouse
- 交叉反應
- All
- 免 疫 原
- A synthetic peptide EETARFQPGYRS conjugated to KLH.
- 產品簡介
- Isotype IgG1
Host Mouse
Reactivity All
SpecificityRecognize C-terminal, internal and N-terminal Tag-100 tagged proteins.
- 產品別名
- -
- 產品成分
- -
- 檢測范圍
- -
- 檢測樣品
- -
- 產品應用
- WB(1:1000-10000)
- 保存條件
- -20°C一年,避免反復凍融。
- 背景資料
- In molecular biology, extracellular-signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. ERKs are known to activate many transcription factors, such as ELK1, and some downstream protein kinases. Disruption of the ERK pathway is common in cancers, especially Ras, c-Raf and receptors such as HER2. Tag-100 tag is an epitope tag composed of a 12-residue peptide, EETARFQPGYRS, derived from the C-termini of mammalian MAPK/ERK kinases.
- 參考資料
- 1.Rao VN, Reddy ES (July 1994). "elk-1 proteins interact with MAP kinases". Oncogene 9 (7): 1855–60.