產品名稱：Polyclonal Anti- Ki67 antibody
- 產品編號
- BRM1103
- 產品規格
- 100ul
- 價格
- 5200.00
- 來源
- human Ki67
- 交叉反應
- -
- 免 疫 原
- -
- 產品簡介
- Catalog# BRM1103
Lot # Check on the product label
Size 100 μl
Isotype IgG
Host Rabbit
Reactivity Human, mouse, rat
Immunogen A synthesized peptide derived from human Ki67, corresponding to a region within the internal amino acids.
Purification Affinity chromatography
Content Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Recommend Application
Western Blot, WB (1:250-1:1000)
ELISA(peptide) (1:10000-1:20000)
Immunohistochemistry,IHC(1:25-1:100)
Immunocytochemistry, ICC/IF (1:50-250)
Other applications have not been tested.
The optimal dilutions should be determined by end user.
Storage Instruction
Ship at 2-8°C, when receipt, aliquot and store at -20°C for one year.
Avoid repeated freeze and thaw cycles.
Background
Antigen KI-67 also known as Ki-67 or MKI67 is a protein that in humans is encoded by the MKI67 gene (antigen identified by monoclonal antibody Ki-67). Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore, it is associated with ribosomal RNA transcription. Ki-67 protein is a cellular marker for proliferation. The role of Ki-67 as a prognostic biomarker has not been established in gastric cancer. High Ki-67 expression in localized PCa is a factor of poor prognosis for DSS, biochemical failure-free survival, DFS, DM, and OS after curative-intent treatments. Incorporation into clinical routine of this widely available and standardized biomarker should be strongly considered.
Reference
1. Berlin A, Castro-Mesta JF, Rodriguez- Romo L, Hernandez- Barajas D, González- Guerrero JF, Rodríguez- Fernández IA, González- Conchas G, Verdines-Perez A, Vera-Badillo FE. Prognostic role of Ki-67 score in localized prostate cancer: A systematic review and meta-analysis. Urol Oncol. 2017 Jun 22. pii: S1078-1439(17)30214-4.
2. Ko GH, Go SI, Lee WS, Lee JH, Jeong SH, Lee YJ, Hong SC, Ha WS. Prognostic impact of Ki-67 in patients with gastric cancer-the importance of depth of invasion and histologic differentiation. Medicine (Baltimore). 2017 Jun;96(25):e7181.
- 產品別名
- 產品成分
- -
- 檢測范圍
- -
- 檢測樣品
- -
- 產品應用
- IgG
- 保存條件
- hip at 2-8°C, when receipt, aliquot and store at -20°C for one year.
- 背景資料
- Antigen KI-67 also known as Ki-67 or MKI67 is a protein that in humans is encoded by the MKI67 gene (antigen identified by monoclonal antibody Ki-67). Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore, it is associated with ribosomal RNA transcription. Ki-67 protein is a cellular marker for proliferation. The role of Ki-67 as a prognostic biomarker has not been established in gastric cancer. High Ki-67 expression in localized PCa is a factor of poor prognosis for DSS, biochemical failure-free survival, DFS, DM, and OS after curative-intent treatments. Incorporation into clinical routine of this widely available and standardized biomarker should be strongly considered.
- 參考資料
- 上一篇：沒有了
- 下一篇：Annexin?V-FITC/PI??細胞凋亡檢測試劑盒
